WAY-213,613
WAY-213,613[edit | edit source]
WAY-213,613 is a chemical compound that has been studied for its potential effects on the central nervous system. It is classified as a selective serotonin reuptake inhibitor (SSRI) and has been investigated for its potential use in treating depression and other mood disorders.
Chemical Properties[edit | edit source]
WAY-213,613 is a small molecule with a specific chemical structure that allows it to interact with the serotonin transporter (SERT) in the brain. The structure of WAY-213,613 is shown in the image to the right. This interaction inhibits the reuptake of serotonin, thereby increasing its availability in the synaptic cleft and enhancing serotonergic neurotransmission.
Mechanism of Action[edit | edit source]
WAY-213,613 functions primarily by blocking the reuptake of serotonin into the presynaptic neuron. This action is similar to that of other SSRIs, which are commonly used as antidepressants. By preventing the reuptake of serotonin, WAY-213,613 increases the concentration of serotonin in the synaptic cleft, which can help alleviate symptoms of depression and anxiety.
Potential Therapeutic Uses[edit | edit source]
The primary therapeutic interest in WAY-213,613 lies in its potential to treat major depressive disorder and other related conditions. SSRIs like WAY-213,613 are often prescribed for their efficacy in improving mood and emotional stability. However, the specific clinical applications of WAY-213,613 are still under investigation, and it has not been approved for clinical use.
Research and Development[edit | edit source]
Research on WAY-213,613 has primarily been conducted in preclinical settings. Studies have focused on its pharmacokinetics, pharmacodynamics, and potential side effects. The compound's selectivity for the serotonin transporter over other monoamine transporters is a key area of interest, as it may influence its side effect profile and therapeutic efficacy.
Side Effects[edit | edit source]
As with other SSRIs, potential side effects of WAY-213,613 may include nausea, insomnia, sexual dysfunction, and weight gain. The exact side effect profile of WAY-213,613 is not fully characterized, as it has not undergone extensive clinical trials.
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Contributors: Prab R. Tumpati, MD
