WNT2

WNT2 is a gene that encodes a member of the WNT family of signaling proteins. These proteins are involved in a variety of developmental processes, including cell growth, differentiation, and tissue formation. Mutations in this gene have been associated with a number of diseases, including autism and schizophrenia.

Function

The WNT2 gene is part of the WNT gene family. This family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis.

Clinical significance

Mutations in the WNT2 gene have been associated with a number of diseases. For example, some studies have suggested a link between mutations in this gene and autism. Other research has indicated that mutations in WNT2 may also be associated with schizophrenia.

See also

• WNT signaling pathway
• WNT gene family

External links

• GeneCards - WNT2