Xibornol

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Xibornol is a bronchodilator used in the treatment of respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). It belongs to the class of mucolytic drugs, which work by thinning and loosening mucus in the airways, clearing congestion, and making breathing easier.

Pharmacology[edit | edit source]

Xibornol's mechanism of action is based on its ability to break down the structure of mucus, making it less viscous and easier to expel from the lungs. This is achieved by breaking the disulfide bonds in the glycoproteins that make up mucus. The drug is typically administered orally, and its effects can be felt within an hour of ingestion.

Clinical Use[edit | edit source]

Xibornol is used in the management of respiratory conditions characterized by excessive mucus production and constriction of the airways. These include chronic conditions such as asthma and COPD, as well as acute conditions like bronchitis and pneumonia. The drug is also used in the treatment of cystic fibrosis, a genetic disorder that causes severe lung damage and respiratory difficulties.

Side Effects[edit | edit source]

Like all medications, Xibornol can cause side effects. Common side effects include nausea, vomiting, diarrhea, and stomach pain. In rare cases, it can cause allergic reactions, which may manifest as rash, itching, severe dizziness, or trouble breathing. Patients are advised to seek immediate medical attention if they experience any of these symptoms.

Contraindications[edit | edit source]

Xibornol is contraindicated in patients with a known hypersensitivity to the drug or any of its components. It should also be used with caution in patients with peptic ulcer disease or those with a history of gastrointestinal bleeding, as it can potentially exacerbate these conditions.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD