Dapagliflozin/metformin

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Dapagliflozin/Metformin is a combination drug used for the treatment of Type 2 diabetes. It is a combination of two active ingredients, Dapagliflozin and Metformin, both of which are oral diabetes medicines that help control blood sugar levels.

Etymology[edit | edit source]

The name "Dapagliflozin" is derived from the chemical name (2S,3R,4R,5S,6R)-2-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. The name "Metformin" is derived from the chemical name N,N-dimethylimidodicarbonimidic diamide.

Mechanism of Action[edit | edit source]

Dapagliflozin works by helping the kidneys get rid of glucose from your bloodstream. Metformin lowers glucose production in the liver, delays glucose absorption from intestines and improves the body's sensitivity to insulin.

Side Effects[edit | edit source]

Common side effects of Dapagliflozin/Metformin include respiratory tract infection, urinary tract infection, and upset stomach. Serious side effects may include lactic acidosis, ketoacidosis, kidney problems, low blood sugar, and genital yeast infections.

Related Terms[edit | edit source]

See Also[edit | edit source]

Dapagliflozin/metformin Resources

Contributors: Prab R. Tumpati, MD