Yamagiwa Katsusaburō

Yamagiwa

Yamagiwa Katsusaburō (山極 勝三郎, February 23, 1863 – March 2, 1930) was a prominent Japanese pathologist and medical researcher. He is best known for his pioneering work in cancer research, particularly for demonstrating the induction of cancer in laboratory animals.

Early Life and Education

Yamagiwa was born in Tokyo, Japan. He pursued his medical education at the University of Tokyo, where he later became a professor. His early work focused on pathology and the study of diseases.

Career and Research

Yamagiwa's most significant contribution to medical science was his research on the causes of cancer. In 1915, along with his colleague Kōichi Ichikawa, he successfully induced cancer in laboratory rabbits by applying coal tar to their skin. This groundbreaking experiment provided the first experimental evidence that chemical substances could cause cancer, laying the foundation for the field of carcinogenesis.

Induction of Cancer

The experiment conducted by Yamagiwa and Ichikawa involved the repeated application of coal tar to the ears of rabbits. Over time, the rabbits developed malignant tumors, proving that exposure to certain chemicals could lead to cancer. This work was crucial in understanding the environmental and chemical factors involved in the development of cancer.

Legacy

Yamagiwa's work had a profound impact on the field of oncology and cancer research. His findings influenced subsequent research on the role of carcinogens and the mechanisms of cancer development. He is remembered as a pioneer in the study of cancer and his contributions continue to be recognized in the medical community.

Personal Life

Yamagiwa was known for his dedication to his research and his students. He spent much of his life in Tokyo, where he continued to work and teach until his death in 1930.

See Also

• Carcinogenesis
• Oncology
• University of Tokyo
• Pathology