ZNF238

ZNF238 (also known as Zinc Finger Protein 238) is a protein that in humans is encoded by the ZNF238 gene. This protein is a member of the zinc finger family of proteins, which are characterized by the presence of zinc finger domains. These domains are known to bind to specific sequences of DNA, playing a crucial role in gene regulation.

Function

ZNF238 is a transcription factor, meaning it helps control the expression of other genes. It does this by binding to specific sequences of DNA in the genome, thereby influencing the rate at which these genes are transcribed into RNA. The exact function of ZNF238 is not fully understood, but it is believed to play a role in cell differentiation and development.

Structure

The ZNF238 protein contains several zinc finger domains. These are small protein motifs that contain a simple beta-beta-alpha structure, held together by a zinc ion. The zinc finger domains of ZNF238 allow it to bind to DNA and regulate gene expression.

Clinical Significance

Mutations in the ZNF238 gene have been associated with various diseases. For example, some studies have suggested a link between ZNF238 mutations and neurodevelopmental disorders. However, more research is needed to fully understand the clinical significance of this gene.

See Also

• Zinc finger
• Transcription factor
• Gene regulation
• Cell differentiation
• Development

References

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