ZNF259

ZNF259, also known as Zinc Finger Protein 259, is a protein that in humans is encoded by the ZNF259 gene. This protein is a member of the zinc finger protein family, which are regulatory proteins known to bind DNA and influence gene expression.

Function

ZNF259 is a transcription factor that can bind to DNA and regulate gene expression. It is involved in various biological processes, including cell differentiation, cell growth, apoptosis, and immune response. The protein is known to interact with other proteins, such as BRCA1 and p53, which are involved in DNA repair and tumor suppression.

Clinical Significance

Mutations in the ZNF259 gene have been associated with several diseases, including breast cancer, prostate cancer, and coronary artery disease. Studies have shown that variations in this gene can influence the risk of developing these diseases.

Research

Research on ZNF259 is ongoing, with scientists seeking to understand more about its function and its role in disease. This research could potentially lead to new treatments for diseases associated with mutations in this gene.

See Also

• Zinc finger
• Transcription factor
• Gene expression
• DNA repair
• Tumor suppression