Endoxifen
(Redirected from ZONALTA)
Endoxifen is an active metabolite of the drug tamoxifen that is used in the treatment of estrogen receptor-positive breast cancer in pre- and post-menopausal women. It is currently being studied for its potential as a treatment for other types of cancer.
Pharmacology[edit | edit source]
Endoxifen is a selective estrogen receptor modulator (SERM) that has been shown to inhibit the growth of estrogen receptor-positive breast cancer cells. It is also a potent inhibitor of cytochrome P450 2D6 (CYP2D6), an enzyme that is involved in the metabolism of tamoxifen.
Clinical Use[edit | edit source]
Endoxifen is used in the treatment of estrogen receptor-positive breast cancer in pre- and post-menopausal women. It is also being studied for its potential as a treatment for other types of cancer.
Side Effects[edit | edit source]
The most common side effects of endoxifen include hot flashes, nausea, and vomiting. Less common side effects include hair loss, joint pain, and fatigue.
Research[edit | edit source]
Research is currently being conducted to determine the effectiveness of endoxifen in treating other types of cancer. Preliminary results suggest that it may be effective in treating prostate cancer, ovarian cancer, and lung cancer.
See Also[edit | edit source]
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