Zahn infarct
Zahn infarct is a rare, non-necrotic lesion of the liver that occurs due to portal vein thrombosis. It is characterized by localized areas of congestion and hemorrhage in the liver parenchyma, but unlike true infarcts, it does not result in tissue necrosis. Zahn infarct is also known as a "pseudo-infarct" because of this lack of necrosis.
Pathophysiology[edit | edit source]
Zahn infarct occurs when there is obstruction of the portal vein, which leads to impaired blood flow to certain areas of the liver. This results in congestion and stasis of blood, causing the affected liver tissue to appear red and swollen. However, because the liver has a dual blood supply from both the portal vein and the hepatic artery, the tissue does not undergo necrosis as it would in a true infarct.
Causes[edit | edit source]
The primary cause of Zahn infarct is portal vein thrombosis, which can occur due to several underlying conditions:
Clinical Presentation[edit | edit source]
Zahn infarct is often asymptomatic and is usually discovered incidentally during imaging studies or histopathological examination of the liver. In some cases, patients may experience mild abdominal pain.
Diagnosis[edit | edit source]
The diagnosis of Zahn infarct is primarily made through histopathology. On microscopic examination, the affected liver tissue shows congestion and dilated sinusoids without necrosis. The presence of portal vein thrombosis may also be noted.
Treatment[edit | edit source]
No specific treatment is required for Zahn infarct itself, as it does not lead to necrosis or significant liver damage. Management focuses on addressing the underlying cause of portal vein thrombosis, if identified.
Prognosis[edit | edit source]
The prognosis for patients with Zahn infarct is excellent, as the condition does not lead to liver failure or other complications. It is important to manage any underlying conditions that may have contributed to the development of portal vein thrombosis.
See also[edit | edit source]
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