Indacaterol/glycopyrronium bromide/mometasone
(Redirected from Zimbus)
Indacaterol/glycopyrronium bromide/mometasone
Indacaterol/glycopyrronium bromide/mometasone is a combination medication used in the management of chronic obstructive pulmonary disease (COPD) and asthma. This combination includes three active ingredients: indacaterol, glycopyrronium bromide, and mometasone furoate, each contributing to the therapeutic effects of the medication.
Pharmacology[edit | edit source]
Indacaterol[edit | edit source]
Indacaterol is a long-acting beta-2 adrenergic agonist (LABA). It works by stimulating beta-2 adrenergic receptors in the bronchial smooth muscle, leading to bronchodilation. This helps to relieve symptoms such as shortness of breath and wheezing in patients with COPD and asthma.
Glycopyrronium Bromide[edit | edit source]
Glycopyrronium bromide is a long-acting muscarinic antagonist (LAMA). It blocks the action of acetylcholine on muscarinic receptors in the airway smooth muscle, resulting in bronchodilation. This action complements the effects of indacaterol, providing a more comprehensive bronchodilatory effect.
Mometasone Furoate[edit | edit source]
Mometasone furoate is a corticosteroid with anti-inflammatory properties. It reduces inflammation in the airways, decreasing the frequency and severity of asthma attacks and COPD exacerbations. Mometasone works by inhibiting multiple inflammatory cytokines and mediators.
Indications[edit | edit source]
Indacaterol/glycopyrronium bromide/mometasone is indicated for the maintenance treatment of patients with COPD and asthma who require a combination of a LABA, a LAMA, and an inhaled corticosteroid (ICS) to manage their symptoms and reduce the risk of exacerbations.
Administration[edit | edit source]
The medication is typically administered via inhalation using a dry powder inhaler. Patients are advised to use the inhaler as prescribed by their healthcare provider, usually once daily.
Side Effects[edit | edit source]
Common side effects of indacaterol/glycopyrronium bromide/mometasone may include:
- Headache
- Nasopharyngitis
- Cough
- Oropharyngeal pain
Serious side effects can include:
- Paradoxical bronchospasm
- Hypersensitivity reactions
- Cardiovascular effects such as palpitations and tachycardia
Contraindications[edit | edit source]
This combination medication is contraindicated in patients with a known hypersensitivity to any of its components. It should be used with caution in patients with cardiovascular disorders, glaucoma, urinary retention, and other conditions that may be exacerbated by the medication's effects.
Also see[edit | edit source]
- Chronic obstructive pulmonary disease
- Asthma
- Beta-2 adrenergic agonist
- Muscarinic antagonist
- Corticosteroid
| Drug Information | |||
|---|---|---|---|
| Image | |||
| Identifiers
CAS Number ATC Code PubChem DrugBank ChemSpider ID UNII KEGG ChEBI ChEMBL IUPAC Name |
Chemical Data
C H N O Molecular Weight | ||
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
