Zinc finger protein 101

Zinc finger protein 101 (ZNF101) is a protein that in humans is encoded by the ZNF101 gene. This protein is a member of the zinc finger family of proteins, which are characterized by the presence of zinc finger domains. These domains are functional units within the protein that enable it to bind to specific sequences of DNA, thereby regulating gene expression.

Structure

ZNF101 is a nuclear protein that contains several C2H2-type zinc fingers. The C2H2-type zinc finger is a common type of zinc finger and is characterized by two cysteine residues and two histidine residues that coordinate a zinc ion. The zinc finger domains of ZNF101 are responsible for its ability to bind to DNA and regulate gene expression.

Function

ZNF101 is believed to act as a transcription factor, meaning it can bind to specific sequences of DNA and regulate the transcription of genetic information from DNA to mRNA. By doing so, ZNF101 can influence the activity of various genes and thereby play a role in a variety of biological processes.

Clinical significance

While the exact role of ZNF101 in human health and disease is not fully understood, it is thought that mutations in the ZNF101 gene could potentially lead to various health conditions. For example, alterations in the function of ZNF101 could potentially disrupt normal gene regulation, leading to abnormal cell growth and potentially contributing to the development of cancer.

See also

• Zinc finger
• Transcription factor
• Gene expression
• Protein structure