Epidemiology of cancer

Study of the distribution and determinants of cancer in populations

Epidemiology of Cancer

The epidemiology of cancer is the study of the distribution, determinants, and frequency of cancer in human populations. It involves understanding the factors that contribute to the development of cancer, identifying patterns and trends, and evaluating the effectiveness of preventive and therapeutic measures.

Global distribution of cancer deaths, 2004

Incidence and Prevalence

Cancer incidence refers to the number of new cases diagnosed within a specific period, while prevalence refers to the total number of cases, both new and pre-existing, at a given time. The incidence and prevalence of cancer vary significantly across different regions and populations due to factors such as genetics, lifestyle, and environmental exposure.

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Global cancer incidence rates

Age and Cancer

Cancer is predominantly a disease of aging, with the majority of cases occurring in individuals over the age of 50. The risk of developing cancer increases with age due to the accumulation of genetic mutations and the decline in immune surveillance.

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Cancer incidence by age group

Risk Factors

Several risk factors contribute to the development of cancer, including:

• Genetic predisposition: Certain inherited genetic mutations can increase the risk of specific cancers.
• Lifestyle factors: Tobacco use, alcohol consumption, poor diet, and physical inactivity are significant contributors.
• Environmental exposures: Exposure to carcinogens such as asbestos, radiation, and pollution can increase cancer risk.
• Infections: Certain viruses and bacteria, such as human papillomavirus (HPV) and Helicobacter pylori, are linked to cancer.

Preventable Causes

Many cancers are preventable through lifestyle modifications and public health interventions. Smoking cessation, vaccination against HPV and hepatitis B, and regular screenings can significantly reduce cancer incidence.

Preventable causes of cancer in the United States

Common Types of Cancer

The most common types of cancer vary by region and gender. Globally, lung cancer, breast cancer, and colorectal cancer are among the most frequently diagnosed.

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Ten most common cancers worldwide

Gender Differences

Cancer incidence and mortality rates differ between males and females due to biological, environmental, and lifestyle factors. For example, prostate cancer is the most common cancer in men, while breast cancer is the most common in women.

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Most common cancers in males by occurrence

Trends and Patterns

Over the past few decades, cancer incidence and mortality rates have shown varying trends. Advances in early detection, improved treatments, and changes in risk factor prevalence have influenced these patterns. In some regions, cancer mortality rates have declined due to better healthcare access and public health initiatives.

Related Pages

• Cancer prevention
• Cancer research
• Oncology
• Public health