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1,1'-Bis(diphenylphosphino)ferrocene (dppf) is a chemical compound commonly used in chemical research. It contains a ferrocene molecule in its structure, which is a type of organometallic compound. The compound is often used as a ligand in homogeneous catalysis, a field of study in inorganic chemistry.


Structure and Bonding[edit | edit source]

The structure of 1,1'-Bis(diphenylphosphino)ferrocene consists of a ferrocene molecule, which is an organometallic compound consisting of two cyclopentadienyl anions bound to a central iron atom, with two diphenylphosphine groups attached to the cyclopentadienyl rings. The diphenylphosphine groups act as ligands, allowing the compound to form coordination complexes with various metals.

Synthesis[edit | edit source]

The synthesis of 1,1'-Bis(diphenylphosphino)ferrocene involves the reaction of chlorodiphenylphosphine with ferrocene in the presence of a base, such as potassium hydroxide. The reaction proceeds via a nucleophilic substitution mechanism, with the diphenylphosphine groups replacing the hydrogen atoms on the cyclopentadienyl rings.

Applications[edit | edit source]

1,1'-Bis(diphenylphosphino)ferrocene is widely used in homogeneous catalysis, particularly in cross-coupling reactions. It is often used as a ligand in the Palladium-catalyzed coupling reactions, such as the Suzuki reaction, Heck reaction, and Sonogashira reaction. The compound's ability to form stable coordination complexes with palladium makes it an effective catalyst for these reactions.


Safety[edit | edit source]

As with many chemical compounds, 1,1'-Bis(diphenylphosphino)ferrocene should be handled with care. It can cause skin and eye irritation, and may be harmful if swallowed or inhaled. Appropriate safety measures should be taken when handling this compound, including the use of personal protective equipment.

See Also[edit | edit source]


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