From WikiMD's Food, Medicine & Wellness Encyclopedia


1,2-Diaminopropane, also known as propane-1,2-diamine, is an organic compound with the formula C_3H_10N_2. It is a colorless liquid that is miscible with water. This compound is one of the simplest diamines, which are compounds containing two amine groups.

Structure and Properties[edit | edit source]

1,2-Diaminopropane has a molecular formula of C_3H_10N_2 and a molar mass of 74.12 g/mol. The compound consists of a three-carbon alkane chain with an amine group attached to the first and second carbon atoms. It has a density of 0.872 g/cm³, a melting point of -37°C, and a boiling point of 120°C. The compound is highly soluble in water and has a refractive index of 1.441.

Synthesis[edit | edit source]

1,2-Diaminopropane can be synthesized through the hydrogenation of 1,2-dicyanopropane or by the reduction of 1,2-dinitropropane. These methods involve the addition of hydrogen to the precursor compounds, resulting in the formation of the diamine.

Applications[edit | edit source]

1,2-Diaminopropane is used in various chemical syntheses and industrial applications. It serves as a building block for the production of chelating agents, polymers, and pharmaceuticals. The compound is also utilized in the preparation of corrosion inhibitors and as a curing agent for epoxy resins.

Safety[edit | edit source]

1,2-Diaminopropane is classified as a hazardous substance. It is flammable, with a flash point of 27°C and an autoignition temperature of 385°C. The compound is also toxic if ingested, with an LD50 of 200 mg/kg in rats. Proper safety measures, including the use of personal protective equipment (PPE) and adequate ventilation, should be observed when handling this chemical.

See also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD