1-Hexadecanol

1-Hexadecanol

1-Hexadecanol, also known as cetyl alcohol, is a fatty alcohol with the chemical formula C₁₆H₃₄O. It is a white, waxy solid that is insoluble in water but soluble in organic solvents. Cetyl alcohol is commonly used in the cosmetic and pharmaceutical industries as an emulsifier and thickening agent.

Chemical Properties

1-Hexadecanol is a long-chain alcohol with a 16-carbon backbone. Its molecular weight is 242.44 g/mol. The compound has a melting point of approximately 49 °C (120 °F) and a boiling point of 344 °C (651 °F). It is a saturated alcohol, meaning it contains no double bonds in its carbon chain.

Production

Cetyl alcohol can be produced by the reduction of palmitic acid, which is a common fatty acid found in palm oil and other natural fats. Industrially, it is often produced by the hydrogenation of palmitic acid or by the reduction of palmitoyl chloride.

Uses

1-Hexadecanol is widely used in the production of personal care products such as lotions, creams, and shampoos. It acts as an emulsifier, helping to blend oil and water components, and as a thickening agent, providing a smooth texture to the product. In pharmaceuticals, it is used as an excipient in the formulation of tablets and ointments.

Safety

Cetyl alcohol is generally considered safe for use in cosmetics and pharmaceuticals. It is non-toxic and non-irritating to the skin. However, as with any chemical, it should be handled with care to avoid ingestion or contact with the eyes.

Also see

• Fatty alcohol
• Emulsifier
• Palmitic acid
• Cosmetic chemistry