From WikiMD's Food, Medicine & Wellness Encyclopedia

2,4-Diaminopyrimidine is an organic compound with the formula C4H6N4. It is one of the isomers of diaminopyrimidine, a type of pyrimidine derivative. Pyrimidines are aromatic heterocyclic organic compounds similar to benzene and pyridine, containing two nitrogen atoms at positions 1 and 3 of the six-member ring.

Structure and Properties[edit | edit source]

2,4-Diaminopyrimidine is a white crystalline solid at room temperature. It is soluble in water and most organic solvents. The compound has two amino groups (-NH2) attached to the carbon atoms at the 2nd and 4th positions of the pyrimidine ring. This structure is responsible for its basicity and ability to form salts with acids.

Synthesis[edit | edit source]

The synthesis of 2,4-Diaminopyrimidine typically involves the reaction of guanidine with cyanoacetic acid in the presence of a base. The resulting intermediate is then cyclized to form the pyrimidine ring.

Applications[edit | edit source]

2,4-Diaminopyrimidine is used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It is also used in the production of dyes and pigments, and as a corrosion inhibitor in the metal industry.

Safety and Toxicity[edit | edit source]

Like many other pyrimidine derivatives, 2,4-Diaminopyrimidine is potentially toxic and should be handled with care. It may cause irritation to the skin and eyes, and prolonged exposure may lead to more serious health effects.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD