2-Oxoquazepam

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2-Oxoquazepam is a benzodiazepine derivative and one of the metabolites of quazepam. It is less active than its parent compound but still has some anxiolytic properties.

Pharmacology[edit | edit source]

2-Oxoquazepam is a metabolite of quazepam, a benzodiazepine derivative. It is less active than quazepam but still retains some anxiolytic properties. The exact mechanism of action is not fully understood, but it is believed to involve enhancing the effect of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain.

Metabolism[edit | edit source]

2-Oxoquazepam is metabolized in the liver, primarily by the enzyme cytochrome P450 3A4 (CYP3A4). It is then excreted in the urine.

Side effects[edit | edit source]

As with other benzodiazepines, 2-Oxoquazepam can cause side effects such as drowsiness, dizziness, and confusion. It can also cause physical dependence and withdrawal symptoms if used for a long period of time or in high doses.

See also[edit | edit source]

2-Oxoquazepam Resources
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Contributors: Prab R. Tumpati, MD