2-chloroquinoline

2-Chloroquinoline is a chemical compound that belongs to the class of organic compounds known as quinolines and derivatives. These are compounds containing a quinoline moiety, which consists of a benzene ring fused to a pyridine ring to form quinoline.

Structure and Properties

The molecular formula of 2-Chloroquinoline is C9H6ClN. It is a chlorinated derivative of quinoline, with the chlorine atom at the 2-position of the quinoline ring system. The compound is a pale yellow liquid at room temperature.

Synthesis

2-Chloroquinoline can be synthesized through the Skraup reaction, a chemical reaction used to synthesize quinolines. In this reaction, aniline is heated with sulfuric acid, glycerol, and an oxidizing agent. The resulting product is then chlorinated to produce 2-Chloroquinoline.

Applications

2-Chloroquinoline is used as a starting material in the synthesis of various pharmaceutical compounds. It is also used in the production of dyes and in chemical research.

Safety and Toxicity

Like many chlorinated organic compounds, 2-Chloroquinoline is potentially hazardous. It can cause irritation to the skin and eyes, and may be harmful if swallowed or inhaled. Proper safety precautions should be taken when handling this compound.

See Also

• Quinoline
• Skraup reaction
• Chlorinated compounds

References

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