2C-G-NBOMe

2C-G-NBOMe is a psychedelic drug and a derivative of the phenethylamine series of compounds. It is closely related to both 2C-G and NBOMe series of drugs, which are known for their potent psychedelic effects and have been the subject of significant interest within both the scientific community and among users of psychoactive substances. 2C-G-NBOMe, like other compounds in the NBOMe series, acts primarily as an agonist for the 5-HT2A receptor, which plays a crucial role in the regulation of mood, anxiety, and perception.

Chemistry

2C-G-NBOMe belongs to the larger family of 2C drugs, which are named for their two carbon atoms between the benzene ring and the amino group. The chemical structure of 2C-G-NBOMe incorporates the core phenethylamine skeleton, with a methoxybenzyl (NBOMe) group attached to the nitrogen (N) atom of the ethylamine chain, and various substitutions on the benzene ring, characteristic of the 2C family. This modification significantly increases its affinity for the 5-HT2A receptor compared to its parent compound, 2C-G.

Pharmacology

The pharmacological action of 2C-G-NBOMe is primarily through its agonist activity at the 5-HT2A receptor. This receptor is known for its role in the effects of many psychedelics. The exact pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion of 2C-G-NBOMe, are not well-documented, reflecting the substance's status as a novel psychoactive substance (NPS). However, it is understood that the NBOMe modification enhances potency and alters the pharmacological profile compared to the parent 2C compounds.

Effects

The effects of 2C-G-NBOMe are similar to those of other psychedelics in the NBOMe series, including altered perception of time and space, enhanced visual and auditory sensations, and profound changes in thought, mood, and consciousness. Due to its potent nature, the risk of adverse effects, including hallucinogen persisting perception disorder (HPPD), psychosis, and physical health risks, is considered to be higher than with some other psychedelic substances.

Legal Status

The legal status of 2C-G-NBOMe varies by country, with many jurisdictions having moved to control the substance under drug prohibition laws in response to concerns over safety and potential for abuse. It is often classified alongside other NBOMe compounds, which have been subject to international control measures.

Safety

Due to its potent effects and relatively recent appearance on the recreational drug market, the safety profile of 2C-G-NBOMe is not well-established. There have been reports of adverse reactions and hospitalizations related to its use, underscoring the need for caution among those who may come into contact with the substance. The lack of research and reliable information on dosage further complicates the safety assessment of 2C-G-NBOMe.