2C-H-NBOMe

2C-H-NBOMe, also known as NBOMe-2C-H, is a psychoactive compound that belongs to the NBOMe series of psychedelics. It is closely related to other compounds in the NBOMe series, which are derived from the corresponding 2C series of phenethylamines designed by Alexander Shulgin and documented in his book PiHKAL (Phenethylamines I Have Known And Loved). 2C-H-NBOMe acts as a potent agonist for the 5-HT2A receptor, which is thought to be responsible for its psychedelic effects. However, unlike its more famous counterparts such as 25I-NBOMe, 2C-H-NBOMe has been less studied and is not as commonly encountered in the recreational drug market.

Chemistry

2C-H-NBOMe is a derivative of the phenethylamine 2C-H, with the addition of a methoxybenzyl (NBOMe) group. This modification significantly increases its affinity for the 5-HT2A receptor. The full chemical name of 2C-H-NBOMe is 2-([2-(4-iodo-2,5-dimethoxyphenyl)ethylamino]methyl)phenol. Its molecular formula is C17H20INO3, indicating the presence of an iodine atom, which is a characteristic feature of many compounds in the NBOMe series.

Pharmacology

The pharmacological action of 2C-H-NBOMe is primarily through its agonist activity at the 5-HT2A receptor. This receptor is a subtype of the serotonin receptor and plays a significant role in the regulation of mood, anxiety, and perception. Agonism at this receptor is a common mechanism of action for many psychedelic drugs. The exact pharmacokinetic properties of 2C-H-NBOMe, such as its half-life, bioavailability, and metabolism, are not well-documented due to the lack of scientific research on this compound.

Effects

The effects of 2C-H-NBOMe are presumed to be similar to those of other psychedelics in the NBOMe series, including alterations in perception, mood, and thought. Users may experience visual and auditory hallucinations, enhanced emotional experiences, and a distorted sense of time. However, the specific effects, potency, and duration of 2C-H-NBOMe have not been systematically studied, and reports from users are scarce.

Safety and Legality

The safety profile of 2C-H-NBOMe is largely unknown, and like other drugs in the NBOMe series, it may pose significant health risks. There have been reports of severe adverse effects and fatalities associated with the use of NBOMe compounds, including cardiovascular complications, seizures, and acute psychosis. The legal status of 2C-H-NBOMe varies by country, but it has been banned or controlled in several jurisdictions due to concerns over its potential for abuse and harm.

Conclusion

2C-H-NBOMe is a synthetic psychedelic compound with limited scientific research available on its effects, pharmacology, and safety. Its close relation to other compounds in the NBOMe series suggests that it may have potent psychedelic effects, but the lack of data makes it difficult to fully understand its risks and benefits. As with all psychoactive substances, particularly those with unknown safety profiles, caution is advised.