3-MeO-PCE

3-Methoxyeticyclidine (3-MeO-PCE) is a dissociative anesthetic that is similar in effect to phencyclidine (PCP) and ketamine. It is a member of the arylcyclohexylamine class of compounds and was first synthesized in 1979.

Chemistry[edit | edit source]

3-MeO-PCE is an arylcyclohexylamine derivative and shares many of its chemical properties. It is a chiral compound, and both the R and S stereoisomers have been studied. The compound is a methoxy derivative of phencyclidine (PCP) and is structurally similar to methoxetamine (MXE).

Pharmacology[edit | edit source]

The pharmacology of 3-MeO-PCE is not fully understood. It is believed to act primarily as an NMDA receptor antagonist, which means it blocks the action of the NMDA receptor. This is thought to be the mechanism behind its dissociative effects. It may also have activity at other receptors, but this is less well understood.

Effects[edit | edit source]

The effects of 3-MeO-PCE can vary widely depending on the dose and individual's physiology. At lower doses, it can produce feelings of euphoria, derealization, and depersonalization. At higher doses, it can cause hallucinations, delusions, and psychosis. It can also cause physical effects such as nausea, dizziness, and ataxia.

Legal Status[edit | edit source]

The legal status of 3-MeO-PCE varies by country. In some countries, it is a controlled substance, while in others it is legal to possess and use. It is important to check the laws in your country before using this substance.

References[edit | edit source]

3-MeO-PCE Resources
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