3-Methylbutyrfentanyl

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Synthetic opioid analgesic

3-Methylbutyrfentanyl

3-Methylbutyrfentanyl




Chemical nomenclature
IUPAC name N-(1-(2-phenylethyl)piperidin-4-yl)-N-(3-methylbutanoyl)propanamide










Identifiers
CAS Number 14188-81-9
PubChem 44469364


ChemSpider 23274847



ChEMBL 2106060
Chemical data


Chemical formula C23H32N2O1


SMILES CCC(C)C(=O)N(C(=O)CC)C1CCN(CC1)CCc2ccccc2




3-Methylbutyrfentanyl is a synthetic opioid analgesic that is an analog of fentanyl. It is a potent agonist of the mu-opioid receptor, similar to other fentanyl analogs, and is used in research settings to study the effects of opioid receptor activation.

Chemical structure and properties[edit]

3-Methylbutyrfentanyl is chemically similar to fentanyl, with the primary difference being the substitution of a 3-methylbutyryl group for the propionyl group found in fentanyl. This modification results in changes to its pharmacokinetic and pharmacodynamic properties.

Pharmacology[edit]

As a potent mu-opioid receptor agonist, 3-Methylbutyrfentanyl produces effects typical of opioids, including analgesia, euphoria, sedation, and respiratory depression. The potency and efficacy of 3-Methylbutyrfentanyl in activating the mu-opioid receptor are comparable to those of fentanyl, making it a subject of interest in opioid research.

Legal status[edit]

Due to its structural similarity to fentanyl and its potential for abuse, 3-Methylbutyrfentanyl is classified as a controlled substance in many jurisdictions. It is often regulated under analog laws that control substances similar to those already scheduled.

Synthesis[edit]

The synthesis of 3-Methylbutyrfentanyl involves the acylation of the piperidine nitrogen in the fentanyl structure with 3-methylbutyryl chloride. This chemical reaction is typically carried out under controlled laboratory conditions due to the potency and potential hazards associated with fentanyl analogs.

Related compounds[edit]

See also[edit]

Gallery[edit]

  • Chemical structure of 3-Methylbutyrfentanyl
    Chemical structure of 3-Methylbutyrfentanyl

3-Methylbutyrfentanyl[edit]

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