3-Methylbutyrfentanyl
Synthetic opioid analgesic
| 3-Methylbutyrfentanyl | |
|---|---|
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| INN | |
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| CAS Number | 14188-81-9 |
| PubChem | 44469364 |
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| ChemSpider | 23274847 |
| KEGG | |
3-Methylbutyrfentanyl is a synthetic opioid analgesic that is an analog of fentanyl. It is a potent agonist of the mu-opioid receptor, similar to other fentanyl analogs, and is used in research settings to study the effects of opioid receptor activation.
Chemical structure and properties[edit | edit source]
3-Methylbutyrfentanyl is chemically similar to fentanyl, with the primary difference being the substitution of a 3-methylbutyryl group for the propionyl group found in fentanyl. This modification results in changes to its pharmacokinetic and pharmacodynamic properties.
Pharmacology[edit | edit source]
As a potent mu-opioid receptor agonist, 3-Methylbutyrfentanyl produces effects typical of opioids, including analgesia, euphoria, sedation, and respiratory depression. The potency and efficacy of 3-Methylbutyrfentanyl in activating the mu-opioid receptor are comparable to those of fentanyl, making it a subject of interest in opioid research.
Legal status[edit | edit source]
Due to its structural similarity to fentanyl and its potential for abuse, 3-Methylbutyrfentanyl is classified as a controlled substance in many jurisdictions. It is often regulated under analog laws that control substances similar to those already scheduled.
Synthesis[edit | edit source]
The synthesis of 3-Methylbutyrfentanyl involves the acylation of the piperidine nitrogen in the fentanyl structure with 3-methylbutyryl chloride. This chemical reaction is typically carried out under controlled laboratory conditions due to the potency and potential hazards associated with fentanyl analogs.
Related compounds[edit | edit source]
See also[edit | edit source]
Gallery[edit | edit source]
Chemical structure of 3-Methylbutyrfentanyl
3-Methylbutyrfentanyl[edit | edit source]
Structure of 3-Methylbutyrfentanyl
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