3-cyanopyridine

3-Cyanopyridine is an organic compound with the formula C6H4N2. It is a colorless liquid that is used as a precursor to the drug nicotinamide, also known as vitamin B3.

Chemical Structure

3-Cyanopyridine consists of a pyridine ring, which is a six-membered aromatic ring with one nitrogen atom, substituted with a cyanide group at the 3-position. The cyanide group consists of a carbon atom triple-bonded to a nitrogen atom.

Synthesis

3-Cyanopyridine can be synthesized from pyridine via a two-step process. First, pyridine is reacted with sodium cyanide in the presence of an acid to form a pyridinium salt. This salt is then heated to form 3-cyanopyridine.

Uses

The primary use of 3-cyanopyridine is as a precursor to nicotinamide, a form of vitamin B3. Nicotinamide is an essential nutrient for humans and is involved in various biological processes, including DNA repair, cell signaling, and metabolism.

Safety

Like other nitriles, 3-cyanopyridine is toxic and should be handled with care. It can cause skin and eye irritation, and if ingested or inhaled, it can cause harm to the respiratory and digestive systems.

See Also

• Pyridine
• Nicotinamide
• Organic compound
• Cyanide