Cyanide
Cyanide is a highly toxic chemical compound containing a carbon and nitrogen atom triple-bonded together (CN^−). Cyanide poisoning can occur through inhalation, ingestion, or skin contact and has severe health effects, including difficulty breathing, irregular heartbeat, uncontrolled movement, convulsions, coma, and possibly death.
Sources and Forms[edit | edit source]
Cyanide can be found in various forms, including hydrogen cyanide (HCN), which is a colorless, highly volatile, and poisonous gas; and salts such as potassium cyanide (KCN) and sodium cyanide (NaCN), which are colorless crystalline solids. Cyanide is produced naturally by certain bacteria, fungi, and algae, and can be found in varying amounts in plants, including apricot and cherry pits, apple seeds, and some beans.
Cyanide is also used in a variety of industrial applications, including gold and silver mining, electroplating, and chemical manufacturing. It is a byproduct of certain manufacturing processes and can be released into the environment from industrial sources, vehicle emissions, and tobacco smoke.
Toxicity and Health Effects[edit | edit source]
Cyanide inhibits cellular respiration by binding to cytochrome c oxidase, an essential enzyme in the mitochondrial electron transport chain. This prevents cells from using oxygen, leading to cellular hypoxia and eventually cell death. Cyanide poisoning affects all organs but is particularly harmful to the brain and heart, which have high oxygen requirements.
Symptoms of cyanide poisoning depend on the dose, route of exposure, and duration of exposure. Acute cyanide poisoning may cause the following symptoms:
- Headache
- Dizziness
- Nausea and vomiting
- Rapid breathing
- Irregular heartbeat
- Uncontrolled movement
- Convulsions
- Coma
- Death
Treatment[edit | edit source]
Immediate treatment is critical for cyanide poisoning, as it can be rapidly fatal. Treatment options include:
- Removal from the source of exposure and administration of fresh air or oxygen
- Administration of antidotes, such as hydroxocobalamin, sodium thiosulfate, or the cyanide antidote kit (amyl nitrite, sodium nitrite, and sodium thiosulfate)
- Supportive care, including intravenous fluids and respiratory support if necessary
Prevention[edit | edit source]
Preventing cyanide poisoning involves minimizing exposure through proper storage, handling, and disposal of cyanide-containing substances, as well as following safety guidelines in industries that use cyanide. Additionally, monitoring and regulating industrial emissions can help reduce environmental exposure to cyanide.
See Also[edit | edit source]
References[edit | edit source]
External Links[edit | edit source]
- Agency for Toxic Substances and Disease Registry: Toxicological Profile for Cyanide
- CDC - NIOSH Pocket Guide to Chemical Hazards - Cyanide
Summary[edit | edit source]
A compound that contains a nitrogen and a carbon atom bound in a special way. It is very poisonous and affects the ability of our tissues to use oxygen. Health effects are similar whether 5-9 204 CHEMICAL it is breathed, ingested, or come in contact with skin. Symptoms include difficulty breathing, irregular heartbeat, uncontrolled movement, convulsions, coma, and possibly death.
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Contributors: Prab R. Tumpati, MD