4,4'-Methylenebis(2-chloroaniline)

From WikiMD's Food, Medicine & Wellness Encyclopedia

4,4'-Methylenebis(2-chloroaniline) (also known as MOCA) is a chemical compound used in the production of polyurethane products. It is a light yellow to amber colored solid with a faint amine odor.

Etymology[edit | edit source]

The name 4,4'-Methylenebis(2-chloroaniline) is derived from its chemical structure. The "4,4'" refers to the positions of the two chloroaniline groups on the methylene bridge. The "methylene" refers to the CH2 group that links the two chloroaniline groups together. The "bis" indicates that there are two chloroaniline groups in the molecule.

Chemical Properties[edit | edit source]

4,4'-Methylenebis(2-chloroaniline) is a benzene derivative. It is a solid at room temperature and has a melting point of 91-93°C. It is slightly soluble in water and soluble in organic solvents such as ethanol and acetone. It is stable under normal temperatures and pressures but can decompose when heated.

Uses[edit | edit source]

4,4'-Methylenebis(2-chloroaniline) is primarily used as a curing agent in the production of polyurethane products. It is also used in the manufacture of rubber and plastic products, and as a hardener in epoxy resins.

Health Effects[edit | edit source]

Exposure to 4,4'-Methylenebis(2-chloroaniline) can cause serious health effects. It is a known carcinogen and can cause bladder cancer and lung cancer. It can also cause skin and eye irritation, and prolonged exposure can lead to liver and kidney damage.

Regulation[edit | edit source]

Due to its carcinogenic properties, the use of 4,4'-Methylenebis(2-chloroaniline) is heavily regulated. In the United States, the Occupational Safety and Health Administration (OSHA) has set a permissible exposure limit (PEL) of 0.01 mg/m3 over an 8-hour workday.

See Also[edit | edit source]

4,4'-Methylenebis(2-chloroaniline) Resources
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Contributors: Prab R. Tumpati, MD