4-Androstene-3,6,17-trione
4-Androstene-3,6,17-trione (also known as 4-AT and 6-OXO) is a steroid that has been sold on the internet as a dietary supplement. It is one of the few prohormones that remain legal to sell in the U.S. following the Anabolic Steroid Control Act of 2004.
Chemical Structure and Properties[edit | edit source]
4-Androstene-3,6,17-trione is a steroid hormone with a double bond at the 4th and 5th positions and three ketone groups at the 3rd, 6th, and 17th positions. It is a metabolite of dehydroepiandrosterone (DHEA) and androstenedione, two naturally occurring androgens in the human body.
Uses and Effects[edit | edit source]
4-Androstene-3,6,17-trione is marketed as a testosterone booster and estrogen blocker. It is claimed to increase muscle mass and strength, reduce body fat, and improve athletic performance. However, these claims are not supported by scientific evidence. The use of 4-AT as a dietary supplement is controversial due to potential health risks and ethical concerns.
Health Risks and Side Effects[edit | edit source]
The safety of 4-Androstene-3,6,17-trione is not well studied. Potential side effects include gynecomastia, hair loss, acne, and prostate enlargement. Long-term use may lead to liver damage and other serious health problems. The use of 4-AT may also result in a positive drug test for anabolic steroids.
Legal Status[edit | edit source]
In the U.S., 4-Androstene-3,6,17-trione is classified as a dietary supplement and is not regulated by the Food and Drug Administration (FDA). However, it is banned by many sports organizations, including the World Anti-Doping Agency (WADA) and the National Collegiate Athletic Association (NCAA).
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD