4-Chloro-o-toluidine

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4-Chloro-o-toluidine[edit | edit source]

Structural formula of 4-Chloro-o-toluidine

4-Chloro-o-toluidine is an organic compound with the chemical formula C7H8ClN. It is a derivative of toluidine, which is a type of aniline where a methyl group is substituted at the ortho position relative to the amino group. In 4-chloro-o-toluidine, a chlorine atom is further substituted at the para position relative to the amino group.

Chemical Properties[edit | edit source]

4-Chloro-o-toluidine is a chloroaniline, which means it contains both a chloro and an amino group attached to a benzene ring. This compound is a solid at room temperature and is typically used in the form of a powder. It is known for its role as an intermediate in the synthesis of various dyes and pigments.

Synthesis[edit | edit source]

The synthesis of 4-chloro-o-toluidine typically involves the chlorination of o-toluidine. This process requires careful control of reaction conditions to ensure selective substitution at the para position. The reaction is usually carried out in the presence of a catalyst and under controlled temperature conditions to prevent over-chlorination.

Applications[edit | edit source]

4-Chloro-o-toluidine is primarily used in the chemical industry as an intermediate in the production of azo dyes. These dyes are widely used in the textile industry for coloring fabrics. The compound is also used in the synthesis of agrochemicals and pharmaceuticals.

Health and Safety[edit | edit source]

Another view of the 4-Chloro-o-toluidine structure

4-Chloro-o-toluidine is considered a hazardous substance. It is classified as a potential carcinogen, and exposure to this compound should be minimized. Proper safety precautions should be taken when handling this chemical, including the use of personal protective equipment such as gloves and goggles. It is important to follow safety data sheet (SDS) guidelines when working with this compound.

Environmental Impact[edit | edit source]

The production and use of 4-chloro-o-toluidine can lead to environmental concerns, particularly if waste products are not properly managed. It is important to ensure that any waste containing this compound is disposed of in accordance with environmental regulations to prevent contamination of water and soil.

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Contributors: Prab R. Tumpati, MD