4-HO-PiPT

4-HO-PiPT

4-HO-PiPT (also known as 4-Hydroxy-N,N-diisopropyltryptamine) is a psychedelic tryptamine compound and a lesser-known member of the PiPT series of compounds. It is structurally related to psilocin, DMT, and other tryptamines.

Chemistry

4-HO-PiPT is a synthetic compound of the tryptamine class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 4-HO-PiPT is substituted at R4 of its indole heterocycle with a hydroxyl (HO) functional group OH-. It also contains two isopropyl groups bound to the terminal amine RN of its tryptamine backbone (PiPT).

Pharmacology

The pharmacological actions of 4-HO-PiPT are not well-studied. However, like other psychedelics in the tryptamine family, it is thought to act principally as a 5-HT2A receptor agonist. The psychedelic effects are believed to come from 4-HO-PiPT's efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience remains the subject of ongoing scientific investigation.

Effects

The effects of 4-HO-PiPT are reported to be similar to other psychedelic tryptamines. They can include hallucinations, enhanced colors, and altered thinking processes. However, the specific effects can vary greatly depending on the individual, dosage, set, and setting.

Legality

The legality of 4-HO-PiPT varies by country. It is not scheduled under the United Nations' drug conventions, but it may be considered illegal in some countries under analog laws.

See also

• Tryptamine
• Psychedelic drug
• PiPT
• 5-HT2A receptor

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