4-HO-pyr-T

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4-HO-pyr-T


4-HO-pyr-T is a psychedelic tryptamine that is less commonly known in the psychoactive community. It is a structural analog of psilocin, which is the active ingredient in psilocybin mushrooms, also known as "magic mushrooms".

Chemistry[edit | edit source]

4-HO-pyr-T, or 4-hydroxy-N,N-tetramethylenetryptamine, is a synthetic indole alkaloid molecule of the tryptamine class. Tryptamines share a core structure comprised of a bicyclic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 4-HO-pyr-T is substituted at R4 of its indole heterocycle with a hydroxy (HO) functional group OH-. It also contains a tetramethylene group bound to the terminal amine RN of its tryptamine backbone (pyr-T).

Pharmacology[edit | edit source]

The pharmacology of 4-HO-pyr-T is not well-studied. However, like other psychedelics in the tryptamine family, it is thought to produce its effects primarily by binding to serotonin receptors in the brain. It is likely to have a similar safety profile to other tryptamines, but this has not been confirmed in scientific studies.

Effects[edit | edit source]

The subjective effects of 4-HO-pyr-T can vary greatly, depending on the dose and individual's physiology. Users often report intense visual hallucinations, altered thinking processes, and a heightened sense of empathy and sociability. However, it can also cause negative effects such as anxiety, paranoia, and potentially dangerous changes in heart rate or blood pressure.

Legal Status[edit | edit source]

The legal status of 4-HO-pyr-T varies by country. In many places, it is not explicitly illegal but may be considered a controlled substance analogue under certain laws. Always check local regulations before possessing or consuming any psychoactive substance.

See Also[edit | edit source]

Template:Psychoactive substance

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Contributors: Prab R. Tumpati, MD