4-Methyl-AET

From WikiMD's Food, Medicine & Wellness Encyclopedia

4-Methyl-AET (also known as 4-Methyl-alpha-ethyltryptamine) is a psychedelic, stimulant, and entactogen drug of the tryptamine class. It is a structural analog of alpha-ethyltryptamine (AET), from which it differs by the addition of a methyl group at the 4-position of the indole ring.

Chemistry[edit | edit source]

4-Methyl-AET is a synthetic compound of the tryptamine class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 4-Methyl-AET is substituted at R4 of its indole heterocycle with a methyl group. It also contains two ethyl chains bound to the terminal amine RN of its tryptamine backbone.

Pharmacology[edit | edit source]

The pharmacology of 4-Methyl-AET is not well-studied. However, like other drugs in the tryptamine class, it is thought to act primarily as a serotonin receptor agonist. This means it binds to and activates the serotonin receptors in the brain, which are responsible for regulating mood, perception, and cognition.

Effects[edit | edit source]

The effects of 4-Methyl-AET can vary greatly depending on the dose, set, and setting. Common effects reported by users include feelings of euphoria, increased empathy and sociability, enhanced sensory perception, and visual hallucinations. However, it can also cause negative effects such as anxiety, paranoia, and potentially dangerous increases in heart rate and blood pressure.

Legal Status[edit | edit source]

The legal status of 4-Methyl-AET varies by country. In some countries, it is a controlled substance, while in others it is legal to possess for personal use.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD