Alpha-ethyltryptamine

Alpha-ethyltryptamine (α-ethyltryptamine, abbreviated as AET), also known as etryptamine, is a psychoactive drug and research chemical belonging to the tryptamine family. It is known for its psychedelic and entactogenic properties. AET was initially developed as an antidepressant in the 1960s but was discontinued due to its psychoactive effects and potential for abuse. It acts primarily as a serotonin releasing agent (SRA) and has a similar mechanism of action to other psychedelic drugs in the tryptamine class.

History

Alpha-ethyltryptamine was first synthesized in the mid-20th century and explored for its potential as an antidepressant. It was marketed under the brand name Monase in the United States but was withdrawn from the market due to its psychoactive side effects and the emergence of more effective and safer antidepressants. In the years following its removal from the medical market, AET found a place in the psychedelic and research chemical communities.

Pharmacology

The pharmacological action of AET is primarily through its activity as a serotonin releasing agent, which leads to increased levels of serotonin in the synapse. This increase in serotonin levels is responsible for its mood-lifting and empathogenic effects. AET also acts on other neurotransmitter systems, but its exact mechanism of action is not fully understood.

Effects

The effects of alpha-ethyltryptamine are similar to those of other psychedelics and entactogens. Users report experiences of enhanced mood, increased empathy, and altered perception of time and space. Visual alterations and hallucinations can also occur, along with introspective insights. The duration of effects typically lasts from 4 to 6 hours when ingested.

Legal Status

The legal status of AET varies by country. It has been classified as a controlled substance in some jurisdictions, which makes its manufacture, distribution, and possession illegal. In other areas, it remains unregulated, existing in a legal gray area for research and personal use.

Safety

As with other psychoactive substances, the safety profile of alpha-ethyltryptamine is not fully established. Potential risks include psychological dependence, neurotoxicity, and adverse psychological effects, particularly in individuals with pre-existing mental health conditions. It is important for users to exercise caution and adhere to harm reduction practices when experimenting with AET.