4-androstenediol

4-Androstenediol (also known as 4-AD) is a androstenediol that is converted to testosterone. The conversion rate is about 15.76%, making it significantly more potent than almost all other legal transdermal hormonal products on the market. It is used for its anabolic effects and is available as a dietary supplement. However, it is not an ideal source of testosterone since it is not very potent.

Structure and Synthesis

Chemical structure of 4-Androstenediol

4-Androstenediol is structurally similar to androstenedione with the exception of the position of the hydroxyl group. It is synthesized from androstenedione through the action of the enzyme 17β-hydroxysteroid dehydrogenase.

Mechanism of Action

4-Androstenediol is converted into testosterone via the enzyme 17β-hydroxysteroid dehydrogenase. Testosterone is a potent androgen that is responsible for the development and maintenance of male secondary sexual characteristics. It also has anabolic effects, promoting the growth of muscle and bone.

Uses

4-Androstenediol is used as a performance-enhancing supplement by athletes and bodybuilders due to its anabolic effects. However, its use is controversial due to potential health risks and ethical considerations.

Side Effects

Potential side effects of 4-Androstenediol include gynecomastia, acne, and prostate enlargement. Long-term use can lead to serious health problems such as liver damage and cardiovascular disease.

Legal Status

In many countries, including the United States, 4-Androstenediol is classified as a controlled substance and its sale and use are restricted.

See Also

• Androstenedione
• Testosterone
• Anabolic steroid

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