5-MeO-DBT

5-MeO-DBT

5-MeO-DBT (5-Methoxy-N,N-dibutyltryptamine) is a psychedelic and hallucinogenic drug, used primarily for its psychoactive effects. It is a derivative of tryptamine, a monoamine alkaloid found in plants, fungi, and animals.

Chemistry

5-MeO-DBT is a synthetic compound of the tryptamine class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 5-MeO-DBT is substituted at R5 of its indole heterocycle with a methoxy (MeO) functional group CH3O−; it also contains two butyl chains attached to the terminal amine RN of its tryptamine backbone (DBT).

Pharmacology

The pharmacological action of 5-MeO-DBT is primarily through its activity at the 5-HT2A receptor. The 5-HT2A receptor is responsible for the cognitive, perceptual, and other mental effects that are characteristic of hallucinogens. The exact nature of 5-MeO-DBT's psychoactive effects, and its relative potency compared to other tryptamines, is not well documented.

Effects

The effects of 5-MeO-DBT are similar to other psychedelic drugs, including visual hallucinations, altered thought processes, and a sense of detachment from reality. These effects can be intense and profound, and can lead to deep introspection, euphoria, and sometimes dysphoria. The duration of effects is typically several hours, but this can vary depending on the dose and individual metabolism.

Legal Status

The legal status of 5-MeO-DBT varies by country. In some countries, it is a controlled substance, while in others it is legal to possess for personal use. It is always important to understand the legal implications of possessing or using 5-MeO-DBT.

See Also

• Tryptamine
• Psychedelic drug
• Hallucinogen
• 5-HT2A receptor