5-MeO-PiPT

5-MeO-PiPT

5-MeO-PiPT (5-Methoxy-N,N-diisopropyltryptamine) is a psychedelic and hallucinogenic drug, part of the tryptamine family. It is less common than other psychedelic tryptamines such as DMT, 5-MeO-DMT, or Psilocin.

Chemistry

5-MeO-PiPT is a synthetic compound of the tryptamine class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 5-MeO-PiPT is substituted at R5 of its indole heterocycle with a methoxy (MeO) functional group CH3O−; it also contains two isopropyl groups bound to the terminal amine RN of its tryptamine backbone (PiPT).

Pharmacology

The method of action for 5-MeO-PiPT, like many other psychedelic tryptamines, is primarily through the serotonin receptors, specifically the 5-HT2A receptor. The drug acts as a non-selective serotonin receptor agonist, which means it binds to and activates multiple types of serotonin receptors in the brain. This leads to an increase in serotonergic activity, which is thought to be responsible for the drug's psychedelic effects.

Effects

The effects of 5-MeO-PiPT can vary greatly depending on the dose, set, and setting. Common effects reported by users include visual hallucinations, enhanced sensory perception, emotional introspection, and a sense of euphoria. Some users also report experiencing negative effects such as anxiety, paranoia, and uncomfortable body sensations.

Legality

The legality of 5-MeO-PiPT varies by country. In some countries, it is a controlled substance, while in others it is legal to possess for personal use. It is always recommended to check the legal status of a substance in your country before possession or use.

See Also

• Tryptamine
• Psychedelic drug
• Hallucinogen
• Serotonin receptor agonist

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