5-Methoxymethylone
5-Methoxymethylone is a psychoactive drug of the phenethylamine, amphetamine, and cathinone chemical classes. It is structurally related to methylone, a designer drug reported to induce entactogenic effects.
Chemistry[edit | edit source]
5-Methoxymethylone, also known as 2-A1MP, is a compound of the substituted cathinone class. Substituted cathinones are modified based on the structure of cathinone, an alkaloid found in the Khat plant. The structure of 5-Methoxymethylone comprises a phenethylamine core with an alkyl group attached to the alpha carbon, and a ketone group attached to the beta carbon. It is further substituted by a methoxy group at the 5th carbon, hence the name 5-Methoxymethylone.
Pharmacology[edit | edit source]
The pharmacology of 5-Methoxymethylone involves action as a serotonin, norepinephrine, and dopamine releasing agent (SNDRA). It is capable of increasing the levels of these neurotransmitters in the brain by inhibiting their reuptake into neurons and promoting their release from neuron storage sites.
Effects[edit | edit source]
The effects of 5-Methoxymethylone are reported to be similar to those of other stimulants and entactogens. These may include feelings of euphoria, increased sociability, mental and physical stimulation, and enhanced empathy and emotional warmth. However, it may also produce adverse effects such as anxiety, paranoia, and overstimulation.
Legal Status[edit | edit source]
The legal status of 5-Methoxymethylone varies by country. In some jurisdictions, it is classified as a controlled substance due to its potential for abuse and addiction.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD