5-Nitro-DMT

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5-Nitro-DMT is a psychedelic compound that belongs to the tryptamine family. It is a derivative of Dimethyltryptamine (DMT), a naturally occurring psychedelic substance found in various plants and animals. The "5-Nitro" prefix refers to a nitro group attached to the 5th carbon of the DMT molecule.

Chemistry[edit | edit source]

5-Nitro-DMT is a nitro compound and a member of the tryptamine class of compounds. Tryptamines are characterized by a core structure that includes a bicyclic indole heterocycle attached at R3 to an amino group via an ethyl side chain. In the case of 5-Nitro-DMT, a nitro group is attached at the 5th position of the indole ring.

Pharmacology[edit | edit source]

The pharmacological properties of 5-Nitro-DMT are not well-studied. However, it is known that the effects of tryptamines are primarily mediated by their action on the serotonin receptors in the brain. Specifically, they are thought to act as partial agonists at the 5-HT2A receptor, which plays a key role in the cognitive effects of psychedelics.

Effects[edit | edit source]

The effects of 5-Nitro-DMT are largely unknown due to the lack of scientific research. However, it is speculated that, like other tryptamines, it may produce a range of psychedelic effects such as visual hallucinations, altered thought processes, and changes in the perception of time and space.

Safety[edit | edit source]

The safety profile of 5-Nitro-DMT is not well-established. As with all psychedelics, it is recommended that it be used with caution and under the guidance of a knowledgeable professional. Potential risks may include psychological distress, adverse physiological reactions, and potential interactions with other substances.

Legal Status[edit | edit source]

The legal status of 5-Nitro-DMT varies by country. In many jurisdictions, it is classified as a controlled substance due to its structural similarity to other regulated tryptamines.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD