6,6-Difluoronorethisterone acetate

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6,6-Difluoronorethisterone acetate is a synthetic steroid and a derivative of noretisterone. It is a potent progestogen, and has been studied for potential use in hormonal contraception and hormone replacement therapy.

Chemistry[edit | edit source]

6,6-Difluoronorethisterone acetate is a synthetic estrane steroid and a derivative of testosterone. It is more specifically a derivative of noretisterone (17α-ethynyl-19-nortestosterone), with two fluorine atoms at the C6 position. The compound is a progestogen, or an agonist of the progesterone receptor, the biological target of progestogens like progesterone.

Pharmacology[edit | edit source]

As a progestogen, 6,6-Difluoronorethisterone acetate has the ability to mimic the body's natural progesterone hormones. This can have various effects on the body, including changes in the menstrual cycle, prevention of ovulation, and changes in the lining of the uterus.

Potential Uses[edit | edit source]

6,6-Difluoronorethisterone acetate has been studied for potential use in hormonal contraception. In this context, it would function by preventing ovulation, thereby preventing pregnancy. It has also been studied for potential use in hormone replacement therapy, which is often used to treat symptoms of menopause.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD