6-(2-aminopropyl)benzofuran

6-(2-Aminopropyl)benzofuran (6-APB), also known as benzofury, is a psychoactive drug and research chemical of the phenethylamine and amphetamine classes. It is structurally related to entactogens like MDMA and is often used in research for its potential use in psychotherapy.

Chemistry

6-APB is a furan compound, which distinguishes it from the many other phenethylamine derivatives. It is similar in structure to MDA, but differs in that the 3,4-methylenedioxyphenyl ring system has been replaced with a benzofuran ring. 6-APB is also the unsaturated benzofuran derivative of 6-APDB.

Pharmacology

6-APB is believed to work primarily as a releasing agent for serotonin, norepinephrine, and dopamine. This means it effectively increases the levels of these three neurotransmitters in the brain by binding to and partially blocking the transporter proteins that normally remove those monoamines from the synaptic cleft.

Effects

The effects of 6-APB are usually compared to MDMA, which is more commonly known. Users report feelings of euphoria, empathy, stimulation, and hallucination. However, these effects are often accompanied by nausea, anxiety, and tachycardia.

Legal Status

The legal status of 6-APB varies by country. In some countries, it is a controlled substance, while in others it is considered a research chemical and is not specifically illegal.

See Also

• MDMA
• Amphetamine
• Phenethylamine
• Psychoactive drug
• Research chemical