7-Methyl-α-ethyltryptamine

7-Methyl-α-ethyltryptamine (also known as 7-MeO-α-ET) is a psychedelic and hallucinogenic drug that belongs to the tryptamine class of compounds. It is structurally related to other tryptamine-based substances such as DMT, 5-MeO-DMT, and psilocybin.

Chemistry

7-Methyl-α-ethyltryptamine is a synthetic compound of the tryptamine class. Tryptamines share a core structure comprised of a bicyclic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 7-MeO-α-ET is substituted at R7 of its indole heterocycle with a methyl (CH3) functional group CH3- but also has an ethyl chain attached to the alpha carbon. This alpha-ethyl substitution forms a propylamine chain with the terminal amine R-N.

Pharmacology

The exact mechanism of action of 7-Methyl-α-ethyltryptamine is not fully understood. However, like other tryptamines, it is believed to act primarily as a serotonin receptor agonist. It may also interact with other neurotransmitter systems. The psychoactive effects of 7-MeO-α-ET are believed to come from its efficacy at the 5-HT2A receptor as a partial agonist. However, the role of these interactions and how they result in the psychedelic experience continues to remain an object of scientific elucidation.

Effects

The effects of 7-Methyl-α-ethyltryptamine can vary widely depending on the dose and individual physiology. Common effects reported by users include visual hallucinations, altered thinking processes, and a heightened sense of empathy and sociability. However, negative effects such as anxiety, paranoia, and potentially harmful changes in heart rate and blood pressure can also occur.

Legal Status

The legal status of 7-Methyl-α-ethyltryptamine varies by country. In many jurisdictions, it is classified as a controlled substance, making its manufacture, distribution, and possession illegal. However, in some countries, it is legal to possess for personal use.

See Also

• Tryptamine
• Psychedelic drug
• Hallucinogen
• Serotonin receptor

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