8-Carboxamidocyclazocine

8-Carboxamidocyclazocine is a chemical compound that belongs to the benzomorphan class of opioids. It is a potent analgesic and has been used in scientific research to study the opioid receptor system.

Chemistry

8-Carboxamidocyclazocine is a derivative of cyclazocine, a synthetic opioid that was developed in the 1960s. The compound is characterized by a unique structure that includes a seven-membered ring with a nitrogen atom, which is a characteristic feature of the benzomorphan class of opioids.

Pharmacology

8-Carboxamidocyclazocine acts as an agonist at the kappa opioid receptor (KOR), mu opioid receptor (MOR), and delta opioid receptor (DOR). It has been shown to have potent analgesic effects, which are primarily mediated through its action at the KOR.

Research

Research on 8-Carboxamidocyclazocine has contributed to our understanding of the opioid receptor system. Studies have shown that the compound can produce analgesia, sedation, and other effects that are characteristic of opioids. However, it also has some unique properties, such as its ability to produce dissociative effects, which are not typically associated with opioids.

See also

• Benzomorphan
• Cyclazocine
• Opioid receptor

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