ACOT13

From WikiMD's Wellness Encyclopedia

ACOT13 is a gene that encodes the enzyme Acyl-CoA thioesterase 13 in humans. This enzyme is part of the Acyl-CoA thioesterase family, which is involved in the metabolism of fatty acids.

Function[edit | edit source]

The ACOT13 gene provides instructions for making an enzyme that is found in the mitochondria, the energy-producing centers of cells. This enzyme is involved in the breakdown of certain types of fatty acids, specifically very long-chain fatty acids. By breaking down these fatty acids, the enzyme helps to control the amount of fatty acids in cells and tissues.

Clinical significance[edit | edit source]

Mutations in the ACOT13 gene have been associated with a variety of health conditions. For example, some studies have suggested a link between variations in this gene and an increased risk of obesity and type 2 diabetes. However, more research is needed to confirm these findings and understand the exact role of ACOT13 in these conditions.

See also[edit | edit source]

References[edit | edit source]


This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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