Abanoquil

From WikiMD's Food, Medicine & Wellness Encyclopedia

Abanoquil is a drug that was developed for the treatment of arrhythmia, a condition characterized by an irregular heartbeat. It is a non-selective alpha blocker, which means it blocks the action of certain chemicals that tighten the blood vessels, thus allowing blood to flow more smoothly and the heart to pump more efficiently.

Mechanism of Action[edit | edit source]

Abanoquil works by blocking alpha-1 adrenergic receptors. These receptors are found in the heart and blood vessels. When these receptors are blocked, the blood vessels relax and widen, which can lower blood pressure and reduce the workload on the heart.

Development and Clinical Trials[edit | edit source]

Abanoquil was developed by SmithKline Beecham, but its development was discontinued after Phase II clinical trials. The reasons for this are not publicly disclosed, but it is common for drugs to be discontinued at this stage due to lack of efficacy or unacceptable side effects.

Side Effects[edit | edit source]

Like all drugs, Abanoquil can cause side effects. The most common side effects reported in clinical trials were headache, dizziness, and fatigue. Less common side effects included nausea, diarrhea, and insomnia.

See Also[edit | edit source]

Abanoquil Resources
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Contributors: Prab R. Tumpati, MD