Fosinopril
(Redirected from Acecor)
Fosinopril is an angiotensin converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and some types of chronic heart failure. Fosinopril is the only phosphinic acid derivative among the ACE inhibitors.
Pharmacology[edit | edit source]
Fosinopril is a prodrug, meaning it is inactive in its administered form and must be metabolized in the body to its active form, fosinoprilat. This conversion is thought to occur in the liver. Fosinoprilat inhibits the angiotensin converting enzyme (ACE), an enzyme that converts angiotensin I to angiotensin II. Angiotensin II is a potent vasoconstrictor, meaning it narrows the blood vessels. By inhibiting the production of angiotensin II, fosinopril causes a decrease in blood pressure and a reduction in the heart's workload.
Clinical Use[edit | edit source]
Fosinopril is used to treat hypertension (high blood pressure), and to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. It is also used to treat patients with heart failure, and can improve survival in patients with left ventricular dysfunction after a heart attack.
Side Effects[edit | edit source]
Common side effects of fosinopril include cough, dizziness, and headache. Less common side effects can include chest pain, fatigue, and nausea. Serious side effects can include kidney failure, liver failure, and severe allergic reactions.
Interactions[edit | edit source]
Fosinopril can interact with a number of other medications, including potassium supplements, lithium, and certain diuretics. It is important for patients to inform their healthcare provider of all medications they are taking.
See Also[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD