Acetone cyanohydrin

Acetone cyanohydrin

Acetone cyanohydrin (ACH) is an organic compound used primarily in the production of methyl methacrylate, the monomer of polymethyl methacrylate (PMMA). It is a colorless liquid, although impure samples can appear yellow. It is formed by the addition of hydrogen cyanide to acetone.

Production

Acetone cyanohydrin is produced by the reaction of acetone with hydrogen cyanide in the presence of a base, such as sodium hydroxide. The reaction is exothermic and is carried out in a continuous process at temperatures of 15-20°C.

Uses

The primary use of acetone cyanohydrin is in the production of methyl methacrylate. It is also used as a reagent in organic synthesis, particularly in the synthesis of alpha-hydroxy acids, amino acids, and vitamin B6.

Safety

Acetone cyanohydrin is highly toxic and poses a significant risk to human health. It is a potent neurotoxin and can cause severe respiratory and eye irritation. It is also highly flammable and can react violently with strong oxidizing agents.

See also

• Acetone
• Hydrogen cyanide
• Methyl methacrylate
• Polymethyl methacrylate

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