Acetyl chloride

Acetyl chloride is an organic compound with the chemical formula CH3COCl. It is a colorless, corrosive, volatile liquid that is widely used in organic synthesis.

Chemical properties

Acetyl chloride is a reactive compound that is often used as an acetylating agent in the formation of esters and amides. It reacts vigorously with water to produce acetic acid and hydrochloric acid, a reaction that is highly exothermic.

Synthesis

Acetyl chloride can be synthesized by the reaction of acetic acid with thionyl chloride, phosphorus trichloride, or phosphorus pentachloride. It can also be prepared by the reaction of acetic anhydride with hydrochloric acid.

Uses

In the chemical industry, acetyl chloride is primarily used as an acetylating agent. It is used in the synthesis of a wide variety of chemical compounds, including pharmaceuticals, dyes, and polymers. It is also used in the production of acetyl compounds, such as acetylferrocene and acetylcysteine.

Safety

Acetyl chloride is a highly corrosive substance that can cause severe burns and eye damage. It is also harmful if inhaled, and can cause respiratory irritation. Proper safety measures should be taken when handling this compound.

See also

• Acetic acid
• Acetyl group
• Acetylation

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