NPH insulin

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NPH insulin, also known as Neutral Protamine Hagedorn insulin, is a type of insulin used in the treatment of both type 1 and type 2 diabetes. It is an intermediate-acting insulin that is often combined with short-acting insulin for multiple daily injections or used in insulin pumps.

Overview[edit | edit source]

NPH insulin is a cloudy, crystalline suspension of insulin combined with protamine and zinc. The addition of protamine, a protein, slows down the absorption of insulin into the bloodstream, allowing for a longer duration of action compared to regular insulin.

Usage[edit | edit source]

NPH insulin is typically injected subcutaneously, or under the skin, once or twice daily. It can be used alone or in combination with other types of insulin or oral diabetes medications. The dosage and timing of NPH insulin are determined by the individual's blood glucose levels and overall health status.

Side Effects[edit | edit source]

Like all forms of insulin, NPH insulin can cause side effects. The most common side effect is hypoglycemia, or low blood sugar. Other potential side effects include weight gain, allergic reactions, and injection site reactions.

Precautions[edit | edit source]

Before starting NPH insulin, individuals should discuss their medical history with their healthcare provider. This includes any allergies, other medications or supplements they are taking, and any other health conditions they have.

See Also[edit | edit source]

References[edit | edit source]


NPH insulin Resources
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Contributors: Prab R. Tumpati, MD