Adipomastia
Adipomastia, also known colloquially as fatty breasts,[1] is a condition defined as an excess of skin and adipose tissue in the breasts without true breast glandular tissue.[2][3] It is commonly present in men with obesity, and is particularly apparent in men who have undergone massive weight loss.[4][5] A related/synonymous term is pseudogynecomastia.[6] The condition is different and should be distinguished from gynecomastia ("women's breasts"), which involves true glandular breast development in a male.[6] The two conditions can usually be distinguished easily by palpation to check for the presence of glandular tissue.[5][7] Another difference between the conditions is that breast pain/tenderness does not occur in pseudogynecomastia.[4] Sometimes, gynecomastia and pseudogynecomastia are present together; this is related to the fact that fat tissue expresses aromatase, the enzyme responsible for the synthesis of estrogen, and estrogen is produced to a disproportionate extent in men with excessive amounts of fat, resulting in simultaneous glandular enlargement.[4][8]
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Contributors: Prab R. Tumpati, MD