Albifylline

Albifylline.svg

Albifylline is a pharmaceutical drug that belongs to the class of xanthine derivatives. It is primarily used for its vasodilatory properties, which help in the treatment of various vascular diseases. Albifylline is known for its ability to improve blood flow and reduce vascular resistance.

Mechanism of Action

Albifylline works by inhibiting the enzyme phosphodiesterase, which leads to an increase in cyclic adenosine monophosphate (cAMP) levels within cells. This elevation in cAMP results in the relaxation of smooth muscle tissues, particularly in the blood vessels, leading to vasodilation. The increased blood flow helps in alleviating symptoms associated with poor circulation and vascular disorders.

Uses

Albifylline is used in the management of conditions such as:

• Peripheral artery disease
• Chronic venous insufficiency
• Intermittent claudication
• Raynaud's phenomenon

Side Effects

Common side effects of Albifylline may include:

• Nausea
• Headache
• Dizziness
• Gastrointestinal discomfort

Severe side effects are rare but can include:

• Allergic reactions
• Cardiac arrhythmias
• Seizures

Dosage and Administration

Albifylline is typically administered orally in the form of tablets. The dosage varies depending on the severity of the condition and the patient's response to the treatment. It is important to follow the prescribed dosage and consult a healthcare provider for any adjustments.

Precautions

Patients with a history of cardiovascular disease, liver disease, or kidney disease should use Albifylline with caution. It is also important to inform the healthcare provider of any other medications being taken to avoid potential drug interactions.

Related Pages

• Vasodilator
• Phosphodiesterase inhibitor
• Peripheral artery disease
• Chronic venous insufficiency
• Intermittent claudication
• Raynaud's phenomenon