Alfetamine

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Alfetamine


Alfetamine is a stimulant and anorectic drug that is chemically related to amphetamine. It was developed in the 1960s and has been used for the treatment of obesity.

History[edit | edit source]

Alfetamine was first synthesized in the 1960s as part of a wave of new amphetamine-like stimulant drugs that were being developed for use as appetite suppressants. It was marketed for a time under the brand name Alfetra and was available in some countries including the United Kingdom and Australia.

Pharmacology[edit | edit source]

Alfetamine acts as a norepinephrine-dopamine releasing agent (NDRA), with a particular emphasis on the release of dopamine. This is similar to the mechanism of action of other amphetamine-like drugs. It also has some activity as a serotonin releaser, although this is much weaker than its effect on dopamine and norepinephrine.

Medical uses[edit | edit source]

Alfetamine was used for a time as an anorectic drug for the treatment of obesity. However, it has largely been replaced by newer drugs with a better safety profile.

Side effects[edit | edit source]

Like other stimulant drugs, alfetamine can have a range of side effects. These can include insomnia, anxiety, agitation, and psychosis in rare cases. It can also have physical side effects such as increased heart rate and blood pressure.

Legal status[edit | edit source]

Alfetamine is a controlled substance in many countries, including the United States, the United Kingdom, and Australia. It is classified as a Schedule II drug in the United States, indicating that it has a high potential for abuse and dependence.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD