Alpha-1-antitrypsin deficiency

From WikiMD's Wellness Encyclopedia

A genetic disorder characterized by decreased alpha-1 antitrypsin activity in the lungs and blood and deposition of alpha-1 antitrypsin protein in the hepatocytes. These abnormalities result from defective production of alpha-1 antitrypsin and lead to the development of emphysema, cirrhosis, and liver failure.

Alpha-1-antitrypsin deficiency Resources

Contributors: Prab R. Tumpati, MD